Oil and Gas Map of the Middlesboro 30 x 60 Minute Quadrangle, Kentucky

The purpose of the oil and gas map series is to portray the distribution of oil and gas resources in a manner useful to the oil and gas industry and to others interested in subsurface research

ERICA: Enabling real-time mistake detection and corrective feedback for free-weights exercises

National Research Foundation (NRF) Singapore under International Research Centres in Singapore Funding Initiativ

Linking ozone pollution and climate change: The case for controlling methane

Methane (CH4) emission controls are found to be a powerful lever for reducing both global warming and air pollution via decreases in background tropospheric ozone (O3). Reducing anthropogenic CH4 emissions by 50% nearly halves the incidence of U.S. high-O3 events and lowers global radiative forcing by 0.37 W m−2 (0.30 W m−2 from CH4, 0.07 W m−2 from O3) in a 3-D model of tropospheric chemistry. A 2030 simulation based upon IPCC A1 emissions projections shows a longer and more intense U.S. O3 pollution season despite domestic emission reductions, indicating that intercontinental transport and a rising O3 background should be considered when setting air quality goals

Syndromic Diagnosis of Malaria in Rural Sierra Leone and Proposed Additions to the National Integrated Management of Childhood Illness Guidelines for Fever

Many countries in Africa, including Sierra Leone, have adopted artemisinin-based combination therapy as first-line therapy for treatment of patients with malaria. Because laboratory testing is often unavailable in rural areas, the cost-benefit and viability of this approach may depend on accurately diagnosing malaria by using clinical criteria. We assessed the accuracy of syndromic diagnosis for malaria in three peripheral health units in rural Sierra Leone and determined factors that were associated with an accurate malaria diagnosis. Of 175 children diagnosed with malaria on syndromic grounds, 143 (82%) were confirmed by the Paracheck-Pf test. In a multivariate analysis, splenomegaly (P = 0.04) was the only clinical sign significantly associated with laboratory-confirmed malaria, and sleeping under a bed net was protective (P = 0.05). Our findings show that clinical malaria is diagnosed relatively accurately in rural Sierra Leone. Incorporating bed net use and splenomegaly into the national Integrated Management of Childhood Illness guidelines for evaluation of fever may further enhance diagnostic accuracy for malaria

Ground-Water Quality in Kentucky: Fluoride

Fluoride (F-) is an ion of the element fluorine, and is a natural component in most water resources. According to Hem (1989), fluoride concentrations in fresh water are generally less than 1 mg/L (milligrams per liter), and the concentration of fluoride in the world\u27s oceans is about 1.3 mg/L. The source of most fluoride in natural fresh-water resources is various rocks and minerals in bedrock and sediments

Ground Water in the Kentucky River Basin

Most private wells in the Kentucky River Basin are in unconfined or semi-confined bedrock aquifers. Within these aquifers, high-yield zones are irregularly distributed. The most productive wells are drilled into fractured bedrock and alluvium along the Kentucky River floodplain. The data indicate that ground water acts as a buffer to peak and low flows in Kentucky River Basin streams. At current withdrawal rates, ground-water usage does not seem to have an adverse impact on the Kentucky River. Privately owned ground-water sources supply approximately 135,000 people living in the basin-approximately 19 percent of the total population and 36 percent of the rural population. More than 50 percent of residential water supplies in eastern Kentucky rely on ground water. If aquifers are protected from pollution by wellhead protection programs and old wells are retrofitted to prevent direct contamination, then ground water will continue to provide a reliable water supply in many rural areas of the basin. However, for most of the basin, few wells will have yields adequate to supply a large demand. Ground water from present wells will not provide an adequate supply for communities with a population of over a few thousand. Limited discharge data available for springs and large wells in the basin strongly suggest that the potential for ground water to supplement current supplies should not be ignored. Discharge from well fields and springs could be used to augment surface supplies during drought. A better understanding of the distribution and quality of ground-water resources is crucial for the citizens of the basin to fully benefit from ground water

The Grizzly, September 24, 2015

CIE Professors Lend a Hand at Columbia U. • As Rush Week Ends, Greek Numbers Defy Expectations • Getting Back on Track • Healthy Addition: HEP Welcomes Rugby Coach to Faculty Lineup • Improving the Higher Education Experience • UC Student Trains Service Dog on Campus • Students Work with College Communications Office • Main Street Life: Upperclassmen Debate Housing\u27s Pros and Cons • Opinions: The Visit Rates 5 / 10; Extra-curricular Options for Students • Going Pro : Symposium on Sports Business and the Entrepreneurial Mindset Comes to Ursinus • Looking to Three-peathttps://digitalcommons.ursinus.edu/grizzlynews/1671/thumbnail.jp

RiboTag : Ribosomal tagging strategy to analyze cell type specific mRNA expression in vivo

Ribosome tagging has become a very useful in vivo approach for analyzing gene expression and mRNA translation in specific cell types that are difficult and time consuming to isolate by conventional methods. The approach is based on selectively expressing an HA-tagged ribosomal protein in a target cell type and then using antibodies against HA to purify the polysomes and associated mRNAs from the target cell. The original approach makes use of a mouse line (RiboTag) harboring a modified allele of Rpl22 (Rpl22-HA) that is induced by the action of Cre recombinase. The Rpl22-HA gene can also be introduced into the animal by stereotaxic injections of an AAV-DIO-Rpl22-HA that is then activated in Cre-expressing cells. Both methods for tagging ribosomes facilitate the immunoprecipitation of ribosome bound mRNAs and their analysis by qRT-PCR or RNA-Seq. This protocol will discuss the technical procedures and describe important considerations relevant to the analysis of the data